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In Traditional Chinese Medicine (TCM), when there are downturned lines at the corners of the mouth, it can mean life has been disappointing. Of course, not everyone that has had disappointment has those lines, but I sure do. And, life sure has been. Having disappointment after disappointment after disappointment can allow bitterness to set in. What is bitterness? Thefreedicitionary.com defines bitterness as resulting from or expressive of severe grief, anguish, or disappoint